Scientific research finds new ways to control appetite

It is reported that scientists from the Scripps Institute in the United States recently discovered a wonderful catalytic antibody that can effectively help the human body reduce appetite. This antibody mainly acts on a gastric hormone auxin that is related to weight gain and fat accumulation. This discovery undoubtedly provides humans with a new way to use biomedical to treat obesity.

　　This study was led by Jin Yanda and Eric Zorrira, a researcher at the Scripps Institute. It was found that after 24 hours of fasting, the catalytic antibody GHR-11E11 in mice leads to a higher metabolic rate than usual. Yanda said: "Our research shows that this new catalytic antibody can effectively reduce auxin levels to help the human body achieve the goal of successfully losing weight."

　　World Health Organization's most important The new report points out that about 100 million people worldwide are overweight or obese, most of them in developed countries. For example, in the United States, the Health and Nutrition Survey Agency found that between 2003 and 2004, about 66% of adults aged 20 or over were overweight or obese to varying degrees. According to a 2006 study published by the American Medical Association, four out of every five American men aged 40 to 59. Although some non-surgical treatments can reduce obesity, weight gain is still controlled by the body's auxin, which stimulates the body to eat when the body is hungry. They promote weight gain and fat storage through metabolism, reducing fat decomposition. When weight loss is lost, the body will automatically produce more auxin to stimulate the body to eat. Research shows that people Always high auxin level before eating, it will decrease after meals. This cycle of auxin is also related to blood sugar content, insulin content and somatostatin. Scientists have shown that mice without this auxin will not have the desire to eat when they are hungry. In addition, it has been proved that the reduction of auxin receptor can reduce food intake and promote the decomposition of fat in the body to ensure the blood sugar content in the blood.

Jin Yangda This study shows that this catalytic antibody can reduce the serum auxin content to regulate energy balance. "We chose to use this method to control obesity because other drug treatments have failed, and using catalytic antibody is the only effective method, which can ensure that weight cannot rebound after stopping treatment. The treatment of obesity must be through less food intake and fat consumption. , This is exactly what this new generation of catalytic antibodies can do. Perhaps some people will worry, because auxin is produced by the human body itself, and will eliminate it have side effects. According to the latest research, the human body itself also produces antibodies that eliminate auxin."

　　This drug treatment for auxin has its own unique advantages. First, it will not have side effects on the central nervous system. Secondly, it works in the blood and will be relatively safer and more effective. 　　Yanda said that given the complexity of obesity treatment, drug treatment based on any antibody must be coordinated with other drugs to achieve a comprehensive treatment including nutrition, psychology, and body and mind. At the same time, he also added that in order for this treatment to work more effectively, scientists need to have a deeper understanding of the long-term effects of catalytic antibodies and their impact on individuals with different weights.